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Labrador Retriever sind klinisch auch im Alter von 6 Jahren noch gut
B-Locus also affects colour of the nose
May-Hegglin Anomaly (MHA) is a hereditary disorder described in Pugs
that causes a symmetric bilateral necrotising myelopathy with tissue softening in the ventral and dorsal white matter
Laktatazidose
D-Lokus (d3) CatCheck Labrador Retriever sind klinisch auchD Locus is responsible for coat colour dilution. Known mutations of the MLPH gene (melanophilin) are responsible for most cases of diluted colours. MLPH gene encodes a protein melanophilin, a key component in the hair and skin pigment formation. A mutation in the gene causes the improper distribution of melanosomes and coat colour dilution. It has an effect on the formation of black eumelanin as well as red yellow pheomelanin, though in lesser extent.
