X-chromosomal Myotubuläre Myopathie (XL-MTM) - Rottweiler Rassebestimmung Mutation: C3 gene

Mutation: C3 gene

Der Zustand

Typical clinical findings include multifocal areas of retinal elevation which progress to multifocal areas of outer retinal atrophy

therefore its excess in urine forms crystals that lead to formation of cystine stones in kidney or bladder

such as vaccination or viral infection

X-chromosomal Myotubuläre Myopathie (XL-MTM) - Rottweiler Rassebestimmung Mutation: C3 geneMyotubular myopathy is a X linked recessive disorder. Affected infant male puppies show signs of facial, axial and proximal neuromuscular weakness with tetraparesis, difficulty holding the head up and a dropped jaw, including hypotonia and areflexia leading to respiratory insufficiency and death within 2 weeks. The symptoms usually occur postnatal and progress very quickly. The affected male puppies have to be euthanised due to progressive symptoms.