A-Lokus Labrador Retriever dog is a carrier of

dog is a carrier of recessive mutation and will transfer it to 50% of its offspring

The disease can affect one or both ears and can be mild

blood in urine

three or four single copy variants of bc

There is currently no specific treatment available for this disease

A-Lokus Labrador Retriever dog is a carrier ofAgouti signal peptide (ASIP) or A Locus is responsible for many different colour patterns in dogs. Specific A Locus allele products can interact with functional MC1R and thus interfere with production of black melanin. Dogs have four different ASIP gene alleles with following dominance hierarchy: Ay > aw > at > a, meaning that the most dominant allele present will be expressed. Genes on A Locus (agouti) are expressed only if a dog on K Locus does not