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It appears in human plasma at approximately 200 ng/ml in young subjects, with a drop of more than 60 % between ages 20 and 60, an observation that motivated forty years of research on its role in tissue repair, wound healing, hair growth and cutaneous longevity

Compr Physiol [Internet]

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doi: 10.1007/s00795-024-00413-z 404

Vorburger SA, Hetrakul N, Xia W, Wilson-Heiner M, Mirza N, Pollock RE, Feig B, Swisher SG , Hunt KK

, University of Kansas 20+ years of clinical experience Dr