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And that is the catch: these drugs do not significantly increase metabolic activity, but instead, by slowing gastric emptying and gut motility (literally moving food around your GI), they very effectively control the primitive urge to gorge

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Tesamorelin directly activates receptors in the pituitary gland, leading to an increase in growth hormone release

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Phase II trials showed mean weight loss of 24.2% at 48 weeks, outperforming all currently approved obesity medications