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doi:10.1111/ejh.12237 Dixon N, Kishnani PS, Zimmerman S
Why We Pair B12 With Folate One of the most important biochemical relationships in the body is between vitamin B12 and folate
HPLC can support purity review, while LC-MS or related mass spectrometry methods can support identity verification when matched with documented reference data [6], [7]
Manifestations and etiologies of vitamin B12 deficiency in adults Vitamin B12 deficiency is relatively frequent in elderly patients, around 2 to more than 30% according to depending on the target population, the design and location of the studies, but is often unrecognized or not investigated because the clinical manifestations of vitamin B12 deficiency are subtle [5]
Allergy to vitamin B12 is uncommon
Both are legitimate, mechanistically coherent, and encouraging as far as they go
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