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Their primary function is to inhibit the conversion of angiotensin I to angiotensin II, leading to vasodilation and a reduction in blood pressure

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In recent years, research has shown that GLP-1s may help with a variety of conditions, including obstructive sleep apnea, heart disease, and chronic kidney disease

If side effects make eating difficult, adjust your food choices and meal timing rather than skipping meals altogether

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These observations are more broadly relevant to drug discovery at peptide GPCRs for which ligand acylation is a valid approach to improve pharmacokinetics