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PubMed Objective: Although the pathogenesis of non-alcoholic fatty liver disease (NAFLD) has been extensively studied, the role of its underlying pathogenesis remains unclear, and there is currently no approved therapeutic strategy for NAFLD
Methotrexate therapy requires adequate folate supplementation (typically 5mg once weekly, taken on a different day from methotrexate) to reduce toxicity
Instead, it mimics a naturally occurring hormone in your gut that communicates with your brain
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