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TPE is performed under the care of a licensed medical provider and monitored by healthcare professionals

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It can cause more swelling and increase the risk of long-term diseases

Methods Complex production and purification Mammalian expression vectors for Fc-IgG1 with A330C mutation and FcRIIIa (V158 allotype) with I106C mutation were prepared separately and individually or co-transfected to ExpiCHO cells (ThermoFisher A29133) according to the manufacturers instructions