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You may need to restart titration from a lower dose to avoid GI side effects when re-introducing the drug

Hristakeva, S., Liaukonyt, J., & Feler, L

The risk of a missed interaction or a subtle disease change going unnoticed increases with medication complexity

The fifth trial, REWIND showed that a weekly injection of 1.5 mg of dulaglutide reduced the risk of cardiovascular outcomes compared with placebo, with benefit starting within the first year of treatment (81)

FDA-approved semaglutide is used for diabetes management and weight-related conditions

Compounded medications are not FDA approved and carry risks related to inconsistent potency, sterility, and formulation quality