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Weeks 5-8 increase to 4mg weekly
An interested stockholder is a person who, together with affiliates and associates, owns or, within three years prior to the determination of interested stockholder status, did own 15% or more of a corporations outstanding voting stock
As STING expression is limited in neoplastic cell populations of gliomas and other CNS tumors, the mechanism of action for STING agonists has mainly focused on immune-mediated anti-cancer activities
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While this doesnt prove earlier-stage efficacy, it does hint that the degree of neurodegeneration, or perhaps neuroplasticity, at baseline may influence the outcome
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