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Several inherent factors within tumor cells and the surrounding tumor microenvironment in the body contribute to chemoresistance, as dose suboptimal chemotherapy dosing (Abdullah 2013

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Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium

Stress may both promote TE movement into eccDNA and enhance TE mobility or amplification once eccDNA forms

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Ferroptosis, an iron-dependent programmed death characterized by the accumulation of lipid peroxide, stands out from the conventional forms of cell death, such as apoptosis, pyroptosis, necrosis, and autophagy