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Cell Biochem
Nadeem et al., 2019)
The findings suggest that SSRIs alter the activities of placental enzymes, which could lead to disturbances in maternal steroid hormone homeostasis and biometabolism, thereby posing a risk to both the developing fetus and the pregnant woman
The peptide binds to vascular endothelial growth factor receptor 2 (VEGFR2), triggering Akt-eNOS signaling that increases nitric oxide production in blood vessel cells
Such peptide-based ProTacs have already been reported 147,148
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