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The accumulation of altered key tumor suppressor genes such as TP53 and CDKN2A, which encode p53 and p16INK4A, respectively is associated with the onset, progression and poor prognosis of HPV-negative HNSCC
In addition, it is an excellent provider of nutrients for a normal immune system
Regular exercise, adequate sleep, and a balanced gut microbiome modulate the incretin pathway, which directly affects metabolic health and weight management
doi: 10.1111/j.1743-6109.2011.02587.x 45 HizOEdizLGlcETekeogluI
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