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But right now, unfortunately, it is unsustainable. The states biggest private insurer, Blue Cross Blue Shield of Massachusetts, also axed coverage of GLP-1 drugs for weight loss this year because the costs were driving up premiums for all members
Crucially, this is the same route used in the clinical research behind these ingredients (7)
A meta-analysis covering over 28,000 patients found that while the overall rate of GI adverse events was similar (approximately 5253% of patients in both groups), serious adverse events occurred somewhat more frequently with higher tirzepatide doses (5.37% at 1015 mg) compared to semaglutide (2.8%)
doi: 10.1016/S0300-483X(00)00231-6 52 DworskiRMurrayJJRobertsLJOatesJAMorrowJDFisherLet al
Even though this dose is nearly 500 times the RDA, it seems to be very common
GLP-1 medications may carry risks, including potential risk of thyroid C-cell tumors
