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Among these models, PBPK modeling can be useful for assessing DDIs caused by different mechanisms of action
Interplay of -Synuclein Oligomers and Endoplasmic Reticulum Stress in ParkinsonS Disease: Insights into Cellular Dysfunctions
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PubMed Research indicates that retinol shows promise in addressing dermal fibroblast senescence, which is a central mechanism of skin aging involving telomere shortening, mitochondrial decline, and dysregulation of signaling pathways
The mechanism for bronchospasm remains speculative but may involve NO-mediated bronchiolar smooth-muscle relaxation tipping into paradoxical constriction in susceptible individuals
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