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These findings demonstrate that gut-derived GLP-1 secreted postprandially regulates feeding behavior and glucose metabolism via GLP-1Rs expressed on vagal sensory neurons

Conclusion Research into GLP-1 receptor agonists has opened a promising new direction for addiction treatment

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The progression to dual agonists represented by tirzepatide (GLP-1 + GIP) demonstrated that targeting additional metabolic receptors could significantly amplify research outcomes

GLP-1 medications can cause digestive side effects