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Start with a low dose and increase gradually
Rinella ME, Neuschwander-Tetri BA, Siddiqui MS, Abdelmalek MF, Caldwell S, Barb D, et al
Three months of oral LC supplementation in healthy aged women induced ten-fold increase of fasting plasma TMAO, and this level remained elevated for the further 3 months of supplementation [16]
If you lose 4 pounds per week for 6 weeks, you could lose about 24 pounds
This dual effect makes it a promising candidate for muscle growth and metabolic improvement, especially in populations with lipodystrophy (a group of disorders that affect how the body stores fat) or sarcopenia (age-related muscle loss) (15)
PMID: 17108971 [7] HHS / FDA
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