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Local (or topical) estrogenapplied directly to the vaginal or vulvar tissuesmay still be an option for managing genitourinary symptoms, as it has minimal systemic absorption compared to full-body MHT

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J Clin Endocrinol Metab 37(5):826828 Elahi D, Andersen DK, Brown JC et al (1979) Pancreatic alpha-and beta-cell responses to GIP infusion in normal man

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