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K.WolfsR
Matrikines in the regulation of extracellular matrix degradation
Cultured mammalian cells were treated with menadione or BSO: menadione increases oxidation of glutathione, while BSO inhibits synthesis of cellular GSH
Conclusions Survodutide was superior to placebo with respect to improvement in MASH without worsening of fibrosis, warranting further investigation in phase 3 trials
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While tirzepatide's cardiovascular outcomes trial (SURPASS-CVOT) is ongoing and cardiovascular benefits are not yet established, the medication has shown favorable effects on multiple cardiometabolic risk factors
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