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Poranen et al., Structural explanation for the role of Mn2+ in the activity of 6 RNA-dependent RNA polymerase, Nucleic Acids Res., 2008, doi: 10.1093/nar/gkn632
Excessive Fe 2+ impairs the function of pancreatic cells and liver cells through oxidative stress and mitochondrial injury, leading to insulin resistance and affecting NAFLD development ( 2+ , elevates ROS levels, and leads to ferroptosis ( in vitro and in vivo ( Intervention effects of herbs or herbal extracts in regulating ferroptosis on non-alcoholic fatty liver disease Currently, there is no agreed standard or definitive effective drugs for the treatment of NAFLD
Otani, H., Tanaka, O., Kasai, K
Semaglutide effects on cardiovascular outcomes in people with overweight or obesity (SELECT) rationale and design
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