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ShenWGaoCCuetoRLiuLFuHShaoYet alHomocysteine-methionine cycle is a metabolic sensor system controlling methylation-regulated pathological signaling

Many preclinical studies have demonstrated that the expression of key enzymes for GSH synthesis (GCL, SLC7A11, GS) and GSSG reduction-related enzymes (G6PD, NADPH, and GR) is downregulated in myocardium exposed to pathological factors [40, 43,44,45,46,47,48,49,50]

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10.1016/j.bpc.2023.107060 244 RzeteckaN.MatuszewskaE.PlewaS.MatysiakJ.Klupczynska-GabryszakA

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