While some studies found no difference between individuals with T2DM and matched non-diabetic controls (6769), others found plasma DPP-4 activity to be reduced in the patients, and suggested this might reflect a compensatory response to the reduced insulin sensitivity and hyperglycaemia, in an attempt to increase intact incretin hormone concentrations and improve insulin secretion (70, 71)
Arinola, Ganiyu British Biotechnology Journal 2014
I recommend that people with CFS have the Vitamin Diagnostics methylation pathways panel run to find out if they do in fact have a partial methylation cycle block and glutathione depletion before deciding, with their doctors, whether to try this treatment
Examples of potentially problematic additives include high-dose vitamin A, green tea extract, kava, or high-dose niacin
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This natural endocrine "influences melanin production in the skin," West Lake writes