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10.2337/dc10-1006 44 SunH.SaeediP.KarurangaS.PinkepankM.OgurtsovaK.DuncanB

Intermittent use is generally safe under supervision

In general, common side effects of both drugs are mild and manageable

Dual photoluminescence emission carbon dots for ratiometric fluorescent GSH sensing and cancer cell recognition

Plasma DPP-4 activity ( A , C , E , and G ), plasma TG and AUC over 180 minutes ( B , D , F , and H , left and middle), and plasma levels of active GLP-1 before and 10 minutes after olive oil gavage ( B , D , F ,and H , right) during a lipid tolerance test (LTT) in response to water or a gut-selective (14 g/mouse) or systemic (10 mg/kg) dose of sitagliptin in 5-hour fasted 16- to 19-week-old Dpp4 EC+/+ ( A and B , n = 1117/group), Dpp4 EC/ ( C and D , n = 1226/group), Dpp4 EC+/+ (BMT) ( E and F , n = 78/group), and Dpp4 EC/ (BMT) ( G and H , n = 78/group) mice fed a 45% high-fat (HF) diet for 69 weeks

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