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Edited by: Kilberg MS, Haeusinger D
Activation of Tissue Remodeling Proteases GHK-Cu activates matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in a balanced way that facilitates controlled extracellular matrix remodeling breaking down damaged collagen and replacing it with new, organized fibrillar collagen rather than scar tissue
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In human studies, powdered leaf supplements were mostly used
Research from the STEP trials shows that gastrointestinal side effects peak during dose escalation periods and then gradually subside over 1 to 2 weeks at the new dose
PLoS ONE, 7 (9), e46276
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