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Most patients experience gastrointestinal symptoms, including diarrhea, during the initial weeks of treatment or when doses are increased
Remember that 5 to 8 percent body weight in three months is significant and sustainable
Mikelsaar M, Zilmer M
J Clin Endocrinol Metabol 86:15041510 Ben-Amitai D, Laron Z (2009) Insulin-like growth factor-1 (IGF-1) deficiency prevents the appearance of pre-acne and acne (Abstract PO2-186) 8th Joint Meeting of the LWPES/ESPE, New York, 912 Sep 2009
One important limitation: the clinical weight loss results were modest
As skin ages, collagen synthesis declines, leading to wrinkles, sagging, and loss of resilience
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