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Tirzepatide is intended for patients with: A BMI of 30 or higher, or 27+ with a related medical condition Previous failed attempts at weight management No personal or family history of medullary thyroid cancer Struggles with regulating blood sugar levels A desire for a long-term, medically supervised treatment Its not intended for casual or cosmetic weight loss and should only be used under medical supervision

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This may be due to the fact that older adults may already feel more familiar with injections through previous medical treatments and healthcare experiences

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Despite nominal associations between higher neutrophil counts and exacerbators in the MGBB-KAS cohort ( p = 0.028) and lower FVC among exacerbators in the MGBB-LLF cohort ( p = 0.049), no clinical measures differed significantly between exacerbators and non-exacerbators across both cohorts (Fig