Several cardiovascular outcome trials (CVOTs) have also reported that GLP-1 RAs may be associated with mitigating kidney-related outcomes, including albuminuria, decline in eGFR and the risk of end-stage kidney disease, independent of their effects on glycemic control 14,15,17,26,27
If you havent discovered IV hydration you are missing out
the NHS approved Mounjaro for weight loss in 2024 but NHS access is still very limited) Exenatide (Bydureon, for type 2 diabetes) Lixisenatide (Lyxumia, for type 2 diabetes) Dulaglutide (Trulicity, for type 2 diabetes) These medications may be available in tablet or injectable form
The STEP (Semaglutide Treatment Effect in People with obesity) trial program showed that participants using semaglutide 2.4 mg weekly achieved an average weight loss of 12-15% of their initial body weight over 68 weeks, compared to 2-3% with placebo
In addition, nausea may be reduced by eating smaller portions
Cell Rep 42(7):112789 De Solis AJ et al (2024) Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism