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Preventing HGF nitration-dysfunction could also improve the therapeutic effects of investigational HGF drugs for various diseases including liver cirrhosis, chronic renal failure, lung fibrosis, myocardial infarction, arteriosclerosis obliterans, amyotrophic lateral sclerosis (ALS, Lou Gehrigs disease), and acute spinal cord injury 47,48,49,50,51,52,53,54,55
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The only practical research format is a lyophilized (freeze-dried) powder reconstituted with bacteriostatic water and injected subcutaneously or intramuscularly
The results showed that the treatment was safe and well-tolerated, with no adverse events reported
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