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The image below demonstrates the effects of GLP-1 agonists on various systems: The most common adverse drug reactions reported with GLP-1 agonists are as follows: These include: In New Zealand, dulaglutide (Trulicity) was the first approved GLP-1 agonist, made available for the treatment of Type 2 Diabetes in 2021
Losing muscle can lower your resting metabolic rate, making it harder to keep the weight off in the long term
FLOW showed semaglutide reduced major kidney disease events by 24%, strengthening the case for GLP-1 RAs as part of cardiorenal-metabolic care
IgA nephropathy does not almost always lead to dialysis, with current standard of care (RAAS blockade, SGLT2i, BP control), many patients never reach kidney failure