postulated that individuals with lower GPx activity are predisposed to impaired antioxidant protection, which leads to oxidative damage to membrane fatty acid s and functional proteins ( Citation53 Forgione and colleagues had previously hypothesized that GP X 1 deficiency directly induces an increase in vascular oxidative stress, with attendant endothelial dysfunction
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Wharton, S., Blevins, T., Connery, L., Rosenstock, J., Raha, S., Liu, R., Ma, X., Mather, K