They can only be used in a safe, controlled laboratory
They occupy a middle ground between small-molecule compounds and full proteins, which is precisely what makes them useful research tools: peptides are large enough to interact selectively with specific receptors and signaling pathways, yet small enough to synthesize with high structural precision
To counteract amyloid fibril formation that occurs with human Amy, a pair of helix-stabilizing mutations (N14E and V17R) were incorporated into Cagri 2
To view a copy of this licence, visit About this article Cite this article Hsieh, MJ., Lee, CH., Chueh, HY
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Benefits include potentially less sting at injection sites for some peptides