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However, several challenges hinder its large-scale application and industrial adoption

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To assess the association of semaglutide with incident AUD, the study population included 598,803 patients with T2DM who had active medical encounters for T2DM during 12/20175/2021, were for the first time prescribed semaglutide or non-GLP1-1RA anti-diabetes medications (new-user design) during 12/20175/2021(index event), had no diagnosis of AUD on or before the index event and had a diagnosis of at least one of obesity-associated comorbidities (hypertension, hypercholesterolemia, hyperlipidemia, heart diseases, stroke) on or before the index event

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typically $30-150/month if covered Cash-pay options: $1,200-1,350/month without discounts Semaglutide Costs Brand-name list price: Ozempic: ~$1,000/month Wegovy: ~$1,350/month Manufacturer cash-pay (NovoCare): $349/month for either formulation Compounded semaglutide: $199/month through TrimRx With insurance: Variable

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Increasing fiber, fluids, and physical activity usually helps resolve this issue

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