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HIV lipodystrophy patients showed about 15.2% visceral fat reduction at 26 weeks versus placebo, plus favorable lipid and trunk-fat changes

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J Pharm Sci 99:40054012

Predicting nurse turnover for highly imbalanced data using the synthetic minority over-sampling technique and machine learning algorithms

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In 56-week studies, patients taking Contrave alongside diet and exercise lost an average of 5-9% of their body weight, compared to 1-5% with a placebo, meaning the medication contributed roughly 4-5 percentage points of additional weight loss.4,5 About 46% of patients on Contrave achieved at least 5% weight loss by week 16