There are a handful that are backed by science to support minimal amounts of weight loss, but they cant stand in for healthy habits like a nutrient-rich diet and regular movement

Benefits of GLP-1 Drugs Significant weight loss: Users often lose 10-15% of their body weight Improved management of type 2 diabetes Reduced risk of cardiovascular events Potential savings in long-term healthcare costs Drawbacks and Concerns High cost: These drugs can cost over $1,000 per month without insurance Side effects: Nausea, vomiting, and gastrointestinal issues are common Long-term effects are still being studied Increased demand leading to drug shortages Impact on Health Insurance Premiums The rising popularity of GLP-1 drugs is affecting health insurance premiums: Some insurers report large double digit increases in pharmacy costs due to GLP-1 prescriptions This could lead to higher premiums for all policyholders However, long-term savings from reduced obesity-related health issues could offset these increases the data is still not comprehensive enough Are the Costs Worth It

In 2025, researchers reported that GLP-1 medications can reduce the risk of sudden death and hospitalization in people with a common type of heart failure
Ipamorelin pushes the second
Consistency helps your body adjust to the medication's effects
In studies, tirzepatide (Mounjaro/Zepbound) produced greater average weight loss than semaglutide at commonly compared doses