Several lifestyle factors can accelerate the breakdown of the collagen you already have
[3] Neutral endopeptidase 24.11 (NEP 24.11) is a membrane-bound zinc metallopeptidase widely expressed in several tissues, but found in particularly high concentrations in the kidneys, which is also identified accountable for the rapid degradation of GLP-1
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published 1981-1987 in middle-aged chronic insomniacs
eLife , 5 , e10727 Hu, W., Zhang, C., Wu, R., Sun, Y., Levine, A., & Feng, Z
Higher isn't always better, especially if you're just starting out or have sensitive skin