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The effect is cumulative: patients who continue beyond 26 weeks often see continued improvement or stabilization at their new body composition baseline

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Peer review Peer review information Nature Medicine thanks John Wilding and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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Patients following very low-carbohydrate diets alongside Ozempic therapy should be particularly mindful of hydration

While some improvements correlate directly with pounds lost, others appear independent of weight change alone