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It is one of the major endogenous antioxidants directly involved in the reduction of reactive oxygen species (ROS), as well as maintaining the levels of exogenous antioxidants such as vitamins C and E [read more about glutathiones many functions here]
Tirzepatide holds FDA approvals as Mounjaro for type 2 diabetes (2022) and as Zepbound for chronic weight management (2023) and for moderate-to-severe obstructive sleep apnea (2024), and it is EMA-approved as well
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Evidence from type 1 diabetes also points to an increase in GSH utilization, which in itself was associated with poorer glucose control.The perfect storm of obesity, oxidative stress, inflammation, adipocyte dysfunction, and the related metabolic abnormalities may also be linked by glutathione depletion
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Alcoholic Liver Disease (ALD) is the result of the way our body treats alcohol in the liver where alcohol metabolic products lead to the formation of Reactive Oxygen Species (ROS) that harm cells through interacting with fats, proteins, and DNA
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