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If SAM pools remain elevated due to reduced NNMT activity, downstream methylation pathways could theoretically be affected
[27] Additionally, anyone with Lebers hereditary optic neuropathy (a rare inherited eye disease) must avoid cyanocobalamin injections, since B can precipitate rapid worsening of that condition
This creates a unique demand that cannot be met by other amino acids
The human trials used oral tablets or short intravenous dosing
MS confirms that what is present is actually the target compound
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