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Reflecting the 97% amino acid homology between liraglutide and native human GLP-1, liraglutide is significantly less immunogenic than exenatide, with antiliraglutide antibodies detected in only 9% to 13% of treated patients, and no attenuation of liraglutide's efficacy in these patients [62,63]

Wang Z, Zhao Y, Zhang L

But anyone with cancer history should avoid both

Phentermine raises cardiovascular risk markers

NishikawaTMiyaharaEKurauchiKWatanabeEIkawaKAsabaKet alMechanisms of fatal cardiotoxicity following high-dose cyclophosphamide therapy and a method for its prevention

2024), whereas centrally-acting agents like phentermine/topiramate focused solely on appetite pathways, achieving a weight loss of 79% (Coulter et al