Under ischemic and hypoxic conditions commonly seen in coronary artery disease (CAD), cardiomyocytes become particularly susceptible to ferroptosis, resulting in cellular dysfunction and diminished cardiac performance
And in fact, the liver is exceptionally adept at regenerating itself
The observed effects in maximal respiration and reserve capacity most likely occur due to increased glycolysis and consequent augmented flux of pyruvate into the Krebs cycle
Moher, D., Liberati, A., Tetzlaff, J., Altman, D
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