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When B12 is administered in doses which saturate the binding capacity of plasma proteins and the liver, the unbound B12 is rapidly eliminated in the urine
But, different commercial preparations may vary
Most patients don't notice a difference between 25-gauge and 27-gauge
Heres what you need to know about B12 injections and why you must choose a qualified provider to deliver them
Higher doses of vitamin B 12 supplements are recommended for patients taking medications that interfere with its absorption (see Drug interactions)
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