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Weakened cohesion increases the risk of premature chromosome separation, leading to aneuploidy

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BMI 27.0 to 29.9 (overweight with potential eligibility)

Rouas R, Fayyad-Kazan H, El Zein N, Lewalle P, Roth F, Simion A, et al

A pre-training baseline measurement is not able to account for varying training regimens, which have a considerable impact on oxidative stress responses

The submission is supported by the SURPASS-CVOT trial, which showed that Mounjaro reduced the risk of MACEincluding CV death, heart attack, or strokeby 8% compared with Trulicity (p=0.086), demonstrating noninferiority to Trulicity regarding CV risk