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Until high-quality clinical data becomes available, caution and responsible communication may protect people who might follow such advice without medical support

While rare, other risks include: Pancreatitisespecially if youve had it before or have related risk factors Possibly thyroid cancer, as seen in animal studies If you or a family member has a history of medullary thyroid cancer or multiple endocrine neoplasia type 2, your clinician may recommend a different medication

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Not a dietary supplement

Patients should be questioned about their adherence to therapy (such as whether or not they are taking this medication as prescribed) before their dosage is increased A dose of 2 mg/kg per day may be necessary for patients with very severe acne, scarring, or primary symptoms on the trunk