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The SELECT trial, published in the New England Journal of Medicine in 2023, showed that semaglutide reduced major adverse cardiovascular events by 20% in patients with obesity and established cardiovascular disease
Tirzepatide works by signaling on two appetite and metabolic receptors at once
It works the same way as semaglutide, but its effects tend to be smaller, both for weight loss and for blood pressure
Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, reduces appetite by signaling fullness to the brain and slowing stomach emptying
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