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The review notes, however, that the degree to which these benefits are independent of weight loss may vary by condition, and further research is needed to elucidate these mechanisms fully

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CrossRef Gastrointestinal Adverse Effects of GLP-1 and Dual GLP-1/GIP Receptor Agonists: A Comprehensive Update in Diabetic and Obese Populations Nimet Ylmaz, Mehmet Bastemir Diabetes, Metabolic Syndrome and Obesity.2026