452 These mechanisms reveal how mitochondria achieve adaptive radiation remodeling through epigenetic regulation, protein interactions, and organelle crosstalk
In cell-based and animal studies, GHRH-receptor agonism (tesamorelin) and GHS-R1a agonism (ipamorelin) have been reported to engage different intracellular signaling cascades that both terminate in growth-hormone secretion, an arrangement investigators have explored for potentially amplified, rather than simply additive, secretory responses
SilvaERRDHunkaMMda Costa CordeiroHEManso FilhoHC
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The remaining author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest