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In pathological conditions, erythrocytes can adhere to endothelial cells, which promotes the formation of microaggregates with consequent blood flow reduction [50]
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In combination, these antioxidants have synergistic effects, that is, they enhance each others effectiveness
This might explain the common x axis intercept in LineweaverBurk plots 11,17,18 , which resemble a non-competitive inhibition pattern with identical dissociation constants for the inhibitor and substrate 52
It is more convenient but less physiological
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