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The striatum is the primary projection field of these substantia nigra neurons, thus the loss of DA results in insufficient stimulation of striatal dopaminergic D 1 and D 2 receptors ( O -methyltransferase inhibitors, to protect the DA that is formed ( A Role for Angiotensins in Parkinsons Disease Allen et al

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doi: 10.1021/acschembio.9b00939 55 XieYZhuSSongXSunXFanYLiuJet al

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Obtaining the NEAs Seal of Acceptance requires products to not only exclude certain known irritants and allergens (e.g., formaldehyde, shellac, citrus ingredients, etc.) but also meet specific clinical safety testing requirements.5 This means the product needs to be successfully tested for safety using human subjects