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Sulforaphane protects against sodium valproate-induced acute liver injury

Notably, the mechanisms of probiotics may involve modulation of gut microbiota composition, while prebiotics such as inulin-type fructans (ITF) can selectively promote the growth of beneficial bacteria like Bifidobacterium and Lactobacillus, enhancing SCFA production and subsequently improving gut barrier function, insulin sensitivity, and metabolic parameters (99, 110)

Drug Interactions No formal pharmacokinetic drug interaction studies exist

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Comp Biochem Physiol B: Comp Biochem

In addition, the high penetration level through the stratum corneum alone can be explained by the fact that there was no tissue retention from underlying skin that may have limited penetration